Satish Gopal, MD, MPH, directs the cancer program at UNC Project-Malawi. He is the only medical oncologist in Malawi, a nation of more than 18 million people. He has received two developmental and two supplemental awards through the UNC CFAR to support his research. Yet, when his daughter became sick with malaria recently, he paused to question his decision to relocate his family to a resource-limited country. In this op-ed in the Journal of the American Medical Association, he explores how this personal sacrifice is leading to important global health contributions.