Developmental Core Description
The Developmental Core provides mentoring support for early stage investigators who are interested in pursuing an HIV research career. We work collaboratively with other CFAR Cores to identify scientific and career mentors as needed, upon request.
The UNC CFAR Developmental Core provides funding for Traditional Developmental Awards, Notices of Special Interest (NOSIs) including a Secondary Data Analysis NOSI and an HIV-COVID NOSI, and Microgrants to emerging HIV investigators for one year of research. Awards are made for/to one of the following:
-Early stage investigators*
-Experienced investigators new to HIV
A senior mentor is required to assist early stage Awardees in preparing the application, executing the project, preparing a manuscript, and writing a resulting larger grant proposal to the NIH. Research can be basic, translational, clinical, or social/behavioral, and can address treatment, transmission, or prevention. There are several opportunities during the year for Awardees to present their work.
*Early stage investigators are defined as never having served as a PI on an R01 or R01 equivalent grant; holding a terminal degree (e.g. Ph.D., MD); eligible to serve as PI on NIH grant; and employed at UNC, FHI 360, RTI, or a NC HBCU.
The CFAR Developmental Cohort is open to Early Stage Investigators affiliated with the CFAR. The Dev Cohort leverages a wide range of professional development resources, and provides opportunities for its members to receive structured feedback from CFAR leadership on their research. Dev Cohort meetings are held monthly throughout the school year, currently virtually. Each year’s Cohort will participate in grant-writing and manuscript-writing workshops, receive personalized feedback on Specific Aims from each other and established investigators, and be given the opportunity to attend a Q&A session with researchers who serve on NIH review panels. Additional meeting topics are driven by members’ interests and may include partnering with the UNC Health Sciences Library to present seminars on topics such as effective poster design, impact measurement and visualization, and/or choosing where to publish; a nationally-recognized Burnout Prevention Program presented by the UNC Department of Psychiatry; and/or sensitivity training for working with the transgender community.
Tips on choosing a mentor from NIH: https://www.niaid.nih.gov/grants-contracts/tips-choosing-mentor; NIAID guidance for writing a grant application can also be found on-line.
Developmental Core News
Allysha Maragh-Bass (FHI 360), Marie Stoner (RTI International) and John Mitchell (Duke) are the MPIs of a unique 2019 Developmental funding and research collaboration between the UNC and Duke CFARs which targeted PrEP. They presented their collaborative CFAR research today at the UNC IGHID/CFAR Friday morning conference:
This presentation will provide an update and results from a UNC-Duke joint developmental award to understand factors related to HIV risk and Pre-Exposure Prophylaxis (PrEP) service through the voices of youth and community members in Durham. The study had three intersecting aims: 1) to create an adolescent health working group of adults and young people to guide the project, 2) to conduct participatory workshops with young people ages 13-24 to get their perspectives on issues related to HIV prevention and 3) a mixed methods assessment including an anonymous, online survey of adolescents and young adults (age 13-24) and face-to-face interviews about HIV risk, and access to PrEP.”
Kate MacQueen, PhD, MPH
Kathleen (Kate) MacQueen is a Senior Scientist in Global Health Population Research at FHI 360. She has conducted extensive research on the social, behavioral and ethical aspects of biomedical HIV prevention trials globally and domestically, including vaccines, microbicides, vaginal rings and pre-exposure prophylaxis. Community engagement and partnership-building is a key component of her work. Domestically she has led participatory research projects focused on understanding and addressing HIV and other health disparities in Durham, NC. She has extensive collaborative international research experience including South Africa, Lesotho, Ghana, Nigeria, Cameroon, Thailand, and Vietnam. She has worked with a diverse range of populations to understand social, cultural and gender dynamics in their use of HIV prevention products. Dr. MacQueen has a PhD in anthropology from Binghamton University, MPH in health behavior from Emory University, and holds adjunct associate professorships at the University of North Carolina at Chapel Hill in the School of Medicine and the Gillings School of Public Health.
Audrey Pettifor, PhD
Dr. Audrey Pettifor is an epidemiologist whose research focuses on sexual behavior and determinants of HIV/STI infection in sub-Saharan Africa. Her goal is to identify modifiable risk factors and develop novel interventions to prevent new HIV infections—particularly among adolescents and young women.
Dr Pettifor has expertise in sexual behavior, HIV prevention, HIV testing and structural interventions among adolescents and young adults in sub-Saharan Africa, and has published extensively in the area of HIV and sexual behavior among youth in sub-Saharan Africa. Dr Pettifor has worked in South Africa for close to 20 years and has also conducted research in Malawi, Madagascar, Kenya, Zimbabwe and the Demographic Republic of Congo.
Cathy Emrick, MPH
Ms. Emrick serves as the Core liaison for Developmental applications and Awardees. Ms. Emrick has an MPH in Health Behavior and Health Education from UNC, and is the Core Manager For the UNC Center For AIDS Research (CFAR) Developmental Core. She has focused on the HIV epidemic since 1990, working in community-based organizations, state government, and research at UNC.
2021/2022 Developmental Awardees
|Chemtai Mungo, Winter 2021/2022||Abigail Hatcher, Spring 2022||Bonnie Shook-Sa, Winter 2021/2022||Monica Diaz, Fall 2021||Friday Saidi, Fall 2021|
|Prevalence, predictors, and impact of high-risk human papillomavirus (HR-HPV) persistence following thermal ablation among HIV-positive and HIV-negative women in a low- and middle-income country (LMIC)||Towards a therapeutic intervention for pregnant adolescents living with HIV and partner violence||Bridged comparisons of HIV therapeutics||
Pilot study for the assessment of neuroinflammation and neurodegeneration in HIV-associated cognitive impairment
The Impact of Antiretrovirals for HIV Prevention and Treatment on the Vaginal Microbiota of Pregnant Women in Malawi and Zambia
2021/2022 Microgrant Awardees
|AAV delivery of CRISPR/Cas9 genome editor to eradicate HIV provirus in the human brain||Antibacterial resistance in people living with HIV||Travel to an international conference to present the findings of her CFAR Developmental Award||
2021-2022 Supplemental Awardees
|Felicia Browne||Katryna McCoy||Joan Price||Lina Rosengren-Hovee||Anne-Marie Turner|
|Developing Strategies to Improve Engagement in HIV Services among People who use Drugs in the Charlotte Transitional Grant Area||Enhancing Strategies to Engage Providers in Efforts to Eliminate HIV: Project EnSTEP||Evaluation of vaginal microbial and inflammatory dynamics to predict HIV-attributable preterm birth in Zambia||
Conversations that Matter: Increasing provider competence and decreasing stigma toward sexual and gender minority youth
Mapping Uninduced, Intact HIV Proviruses in ART-Suppressed Donors
|Allysha Maragh-Bass||Marie Stoner|
|Formative research on a sex-positive tool for PrEP Counseling with Sexual/Gender Minority Youth of Color in NC and CA||
Request for Proposals for Developmental Awards
The UNC CFAR Developmental Core provides Developmental Awards and small secondary data analysis awards to emerging HIV investigators for one year of research.
Required Documents from new Developmental Awardees:
Acknowledgment of CFAR Developmental Financial Obligations
Human Subjects Study form (initially including Planned Enrollment Form and later, regular updates to the Cumulative Enrollment Form)
Final Developmental application, including budget and budget justification
.pdf copy of IRB approvals from any collaborating institutions as well as UNC
Photo of PI for CFAR website
Documentation of human subjects training for all study personnel
All informed consent forms